What is Midol Caffeine Free?

Midol is a popular over-the-counter pain reliever that specializes in treating many of the symptoms associated with menstruation. It addresses bloating, fatigue, back pain, muscle aches, and headaches. Midol is one of the most well-known products to address period pain and discomfort, and this formula is caffeine free to remove associated side effects like irritability and jitteriness.


The official formula for Caffeine-free Midol is not listed on the company’s websites. The original formula includes:

  • Acetaminophen – 500mg
  • Pyrilamine maleate (an antihistamine) – 15mg
  • Caffeine – 60mg

The caffeine-free formula is likely to contain the same ingredients, except the caffeine. The inactive ingredients include:

  • Carnauba wax
  • Croscarmellose sodium
  • FD&C blue #2 aluminum lake
  • Hypromellose
  • Magnesium stearate
  • Microcrystalline cellulose
  • Pregelatinized starch
  • Propylene glycol
  • Shellac
  • Titanium dioxide
  • Triacetin


Children and adults 12 years and older are instructed to take two tablets every six hours. You should not exceed six tablets in a twenty-four hour period.


On Amazon, Midol Caffein-Free is listed at $5.98 and is eligible for a subscribe-and-save discount. The subscribe-and-save program saves between 5% and 15% off, based on the size of the subscription order. It can also be found in local pharmacies for a similar price, and subject to in-store promotions, as well as from pharmacy websites.

Possible Side Effects

There are many different side effects associated with acetaminophen including nausea, stomach pain, and drowsiness as the most common. The most common side effects of pyrilamine maleate include dizziness, drowsiness, racing heartbeat, nausea, muscle weakness, and loss of appetite. The inactive ingredients can also have adverse side effects. Croscarmellose sodium is dangerous for people who are allergic to gluten. The coloring agent aluminum lake can increase the risk of some cancers.

Manufacturer’s Commitment

There is nothing about a money-back guarantee visible on any part of the company’s website or on Amazon, but it is possible that there could be a return policy if purchased through a local pharmacy.

The Bottom Line

Classic Midol has a high rating of effectiveness, but on Amazon, there is only one review for Midol Caffeine-Free. Though positive, it’s hard to know if this means that the product is equally effective as the original, or if the effectiveness is limited. The lack of caffeine reduces jitteriness many experience with regular Midol. It is easy to find in many different stores, both online and in person, and its low price make it easily accessible. Downsides are the large number of inactive ingredients that can cause adverse reactions, and the more serious side effects of upset stomach and severe drowsiness associated with the active ingredients. Because of the large number of synthetic ingredients, it is also hard to know how each individual will react. Further, those who are intolerant or sensitive to gluten may want to avoid this medicine as it is made in a facility that could be contaminated, and contains trace amounts.

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