What is New Chapter Estrotone?

Estrotone is a daily hormone balance supplement for pre- and post-menopausal women. The product is described as a carefully selected combination of different herbs, vitamins, minerals, and Omega fatty acids, and marketed as a traditional herbal remedy encapsulated.


Two New Chapter Estrotone tablets contain the following active ingredients:

  • 200mg evening primrose oil
  • 160mg schizandra berry extract
  • 50mg ginger extract
  • 40mg black cohosh extract
  • 40mg chaste tree extract
  • 10mg rosemary extract

Other ingredients include:

  • Gelatin
  • Vegetable glycerin
  • Water
  • Carob
  • Extra-virgin olive oil
  • Maltodextrin
  • Yellow beeswax
  • Organic sunflower oil


The product’s directions indicate to take two softgels per day with a meal. If users are on birth control, planning to have surgery, or have certain preexisting conditions, they are instructed to consult with a physician prior to use. In no cases should nursing or pregnant women take this product.


New Chapter lists the Estrotone product on their website in two sizes: 60 and 120 softgel capsules. The product is not available for purchase on the manufacturer’s website, but various online purchasing options are listed from external sellers. Amazon lists prices at $19.19 for the 60-count variant ($0.32 per tablet) and $28.79 for the 120-count variant ($0.24 per tablet).

Possible Side Effects

The website and product label indicate possible side effects that accompany liver trouble, including abdominal pain, dark urine, and jaundice. Importantly, they also instruct users to carefully review the ingredient list and determine if they are sensitive to any of the ingredients. The primary ingredient in Estrotone is primrose oil, which can induce side effects including nausea, upset stomach, headache, and diarrhea. Additionally, allergic reaction to the oil’s plant enzymes may appear for some individuals. Skin rash, itching, throat swelling, dizziness, and difficulty breathing are all indicators of an allergic reaction requiring medical attention.

Manufacturer’s Commitment

The product comes with a 60-day guarantee. However, you will only get your refund in the form of a prepaid card. The details of how to return a product is mentioned on the manufacturer’s website. The instruction for consumers to check over the ingredient list is telling, and indicates that New Chapter is not only ensuring the safety of their users, but also admitting that their product may affect users in different ways.

The Bottom Line

In our review of New Chapter’s Estrotone, we find that it adequately address many of the concerns of pre- and post-menopausal women seeking an herbal remedy to influence their hormone balance. The vast majority of online reviews of Estrotone were very positive, and many people especially noted improvement in the number and severity of hot flash episodes. It’s important to note that user reviews were not uniformly positive: Multiple Amazon reviewers mentioned the product’s ineffectiveness, and a few even wrote of the product causing significant negative side effects. While these reviews must always be taken with a grain of salt, consumers should be cautious when testing the product. Herbal remedies of this nature rely on the quality of the herbs themselves, and manufacturers often deny responsibility for herb quality. Finally, our primary reservation in comparing this product to similar products on the market is its failure to address both the daytime and nighttime symptoms of menopause.

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